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Effect Of Vitamin-E Supplementation On Lead Toxicity In Japanese Quail (Coturnix Japinica)

By: Yaseen Humayun | Dr.Asim Aslam.
Contributor(s): Dr.Kamran | Dr.Muhammad Younas Rana.
Material type: materialTypeLabelBookPublisher: 2011Subject(s): Department of PathologyDDC classification: 1264,T Dissertation note: Quails are farmed in large number in Pakistan. Due to improper manage mental rearing system for quails in Pakistan the chances of lead toxicity is more in country through feed and fences and water. A total number of 420, day old chicks of Japanese quail were procured from the hatchery of Avian Research and Training Centre (ARTC), UVAS, Lahore. They were assigned seven dietary treatments. There were three replicates in each treatment group and each replicate was of twenty chicks. Control diet group A received only basal diet without any supplementation. Group B received basal diet + 50 mg/kg Pb. Group C received basal diet + 75 mg/kg Pb. Group D received basal diet +100 mg/kg Pb. Group E received basal diet+50 mg/kg Pb+40 mg/kg vit-E. Group F received basal diet+75 mg/kg Pb + 40mg/kg vit-E. Group G received basal diet+100 mg/kg Pb + 40mg/kg vit-E. The body weight of each the birds were carried out weekly and significant results were observed. Blood samples were collected on the 21st (3rd week), 28th (4th week), 35th (5th week) and 42nd (6th week) days of dietary treatment from two birds from each group to evaluate the liver, kidney functions and non significant results were observed. In liver mild degeneration of hepatocytes and increase in Kupffer cells while degeneration in the epithelium and mild fibrosis in interstitial tissue and cystic dilatations in the tubules and hyaline casts in the lumens of kidney tubules were major pathological lesions caused by lead and vitamin-E were observed.
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Item type Current location Collection Call number Status Date due Barcode Item holds
Thesis Thesis UVAS Library
Thesis Section
Veterinary Science 1264,T (Browse shelf) Available 1264,T
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Quails are farmed in large number in Pakistan. Due to improper manage mental rearing system for quails in Pakistan the chances of lead toxicity is more in country through feed and fences and water. A total number of 420, day old chicks of Japanese quail were procured from the hatchery of Avian Research and Training Centre (ARTC), UVAS, Lahore. They were assigned seven dietary treatments. There were three replicates in each treatment group and each replicate was of twenty chicks. Control diet group A received only basal diet without any supplementation. Group B received basal diet + 50 mg/kg Pb. Group C received basal diet + 75 mg/kg Pb. Group D received basal diet +100 mg/kg Pb. Group E received basal diet+50 mg/kg Pb+40 mg/kg vit-E. Group F received basal diet+75 mg/kg Pb + 40mg/kg vit-E. Group G received basal diet+100 mg/kg Pb + 40mg/kg vit-E. The body weight of each the birds were carried out weekly and significant results were observed. Blood samples were collected on the 21st (3rd week), 28th (4th week), 35th (5th week) and 42nd (6th week) days of dietary treatment from two birds from each group to evaluate the liver, kidney functions and non significant results were observed. In liver mild degeneration of hepatocytes and increase in Kupffer cells while degeneration in the epithelium and mild fibrosis in interstitial tissue and cystic dilatations in the tubules and hyaline casts in the lumens of kidney tubules were major pathological lesions caused by lead and vitamin-E were observed.

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